Abstract: A pandemic of international concern is Coronavirus disease (Covid-19). It poses significant health risks all over the world and there is no successful cure for it. Usage in studies of silico docking. In this respect the docking evaluation was for active plant constituent ligands. In-silico docking studies have taken the place of the new version of GLIDE Software v5.5, built by Schrödinger. These findings showed that the binding energy in all active components ranged from -3.1 to -8.3 kcal/mol. If compared to the standard (-8.5 kcal/mol). It was found that, as opposed to the standard drugs, the investigated phytoconstituents showed potent inhibiting activity as the MolDock score directly represents possible binding to the enzyme.
Abstract: Dentifrices are products used for oral hygiene, such as mouth freshness and to prevent tooth decay. Using different dentifrices prepared from herbal and synthetic ingredients, oral hygiene can be preserved during the day. Cavity is that by having the most protective measure for the host, most current dental wellness moving mankind spittle acts as a protective problem against cavity growth. Saliva is rich in proteins and amino acids, which help to sustain the oral cavity’s homeostasis. The toothpaste used in this study was made with a range of herbal ingredients that have antibacterial, antiseptic, and cooling properties.
Abstract: Polymorphs of a compound are different crystal forms in which the lattice arrangement of molecules are dissimilar. These distinct solids usually have different melting points, solubilities, densities and optical properties. Many polymorphic compounds have flexible molecules that may assume different shapes of these solids shows that their crystal lattices impose certain conformational constraints. When melted or in solution, different polymorphic crystals of this kind produce the same rapidly equilibrating mixture or molecular species. Polymorphism is similar to, but distinct form, hydrated or solvated crystalline forms. It has been estimated that over many known organic compounds may be capable of polymorphism. Many pharmaceutical compounds exist in different crystalline forms and thus exhibit polymorphism. Polymorphism may affect chemical and Physical Stability, apparent solubility, dissolution, bioavailability and bioequivalence and manufacturability of drug product, which require special attention during product development as it affects the quality, safety and efficacy of drug product. In this article we had performed polymorphism study of some synthesized compounds and identified their shapes by using motic microscope.
Keywords: Polymorphism, Crystalline Forms, Chemical Stability, Motic Microscope.
Abstract: Cosmeceuticals are a new category of products that are put between cosmetics and pharmaceuticals to improve both skin health and appearance. Cosmeceuticals are manufactured from a multitude of ingredients, Cosmetic ingredient and Mushroom cosmetics are discussed in this article. Given the increasing interest among patients in these products and the strong claims made by manufacturers, it is crucial that doctors recognise these agents and consider their advantages, disadvantages, and possible adverse effects.
Abstract: Herbal fast-dissolving tablets (FDTs) are formulated to disintegrate and dissolve quickly in the oral cavity, offering a convenient dosage form for patients who have difficulty swallowing. This study highlights the development and evaluation of polyherbal FDTs containing turmeric, cinnamon, and ginger extracts, utilizing superdisintegrants such as sodium starch glycolate and croscarmellose sodium. The tablets were manufactured using the direct compression method and assessed for parameters including weight variation, hardness, friability, disintegration time, and in vitro dissolution. The findings demonstrated that all formulations complied with pharmacopeial standards, with formulation F4 showing the fastest disintegration time (47.66±1.1 seconds) and the highest drug release within 12 minutes. These results indicate that herbal FDTs are a promising and patient-friendly approach for delivering herbal medicines.
