Abstract: Niosomes are a novel drug delivery system, in which the medication is encapsulated in a vesicle. The vesicle is composed of a bilayer of non-ionic surface active agents and hence the name niosomes. The niosomes are very small, and microscopic in size. Their size lies in the nanometric scale. Although structurally similar to liposome’s, they offer several advantages over them. Niosomes have recently been shown to greatly increase transdermal drug delivery and also can be used in targeted drug delivery, and thus increased study in these structures can provide new methods for drug delivery. In recent years, niosomes have been extensively studied for their potential to serve as a carrier for the delivery of drugs, antigens, hormones and other bioactive agents. Besides this, noisome have been used to solve the problem of insolubility, instability and rapid degradation of drugs.
Keywords: Niosomes, Small Unilamellar Vesicles, Encapsulation, Microfludization, Drug Carriers..