Nanoparticles are used in a number of fields, including antimicrobials, additives, paints, biosensors, and cosmetics. Because of their multifunctional property and intrinsic molecular property, inorganic nanoplatforms are an appealing tool in a range of biomedical applications. They assist in efficient diagnosis, imaging, continuous monitoring, and successful therapy. Bio-reduction of inorganic nanoparticles (INPs) using bacteria and other microorganisms has recently gained popularity due to several advantages over chemical synthesis methods, including low cost, fewer toxic chemicals used, biocompatibility, and ease of synthesising. The use of microbes is an excellent way to deal with the development of environmentally safe and cost-effective nanoparticles. Advancement of nanoparticles union by improved generation of society growth will provide a strong opportunity for the most extreme manufacture, and it will be extremely useful for a variety of nanoparticles-based applications.