Abstract: A pandemic of international concern is Coronavirus disease (Covid-19). It poses significant health risks all over the world and there is no successful cure for it. Usage in studies of silico docking. In this respect the docking evaluation was for active plant constituent ligands. In-silico docking studies have taken the place of the new version of GLIDE Software v5.5, built by Schrödinger. These findings showed that the binding energy in all active components ranged from -3.1 to -8.3 kcal/mol. If compared to the standard (-8.5 kcal/mol). It was found that, as opposed to the standard drugs, the investigated phytoconstituents showed potent inhibiting activity as the MolDock score directly represents possible binding to the enzyme.