Abstract: A hydrogel is a network of polymer chains that don’t dissolve in water. It can also be found as a liquid gel in water. Hydrogels are superabsorbent materials that come from nature or are made in a lab. They can hold over 99 percent water. Because the medicine gets into the lower layers of the skin or mucous membranes, it has affects that are only felt at the place where it is applied. Microemulsions are colloidal dispersions that are thermodynamically stable, fluid, transparent (or translucent), and made up of an oil phase, an aqueous phase, a surfactant, and a co-surfactant in the right amounts to form a single optically isotropic solution with droplet sizes that are usually between 10 and 100 nanometers. Transparency, low viscosity, and, most importantly, the ability to make micro-emulsions that naturally split from regular emulsions. As a way to put medicine on the skin, micro-emulsions are better than creams, gels, and liquids in a number of ways. Based on microemulsion, the Hydrogel technology will be able to keep the effective dose at the site of action while also making the drug more bioavailable. This study looks at how microemulsion-based hydrogel is made, how it is characterised, how it is evaluated, and how stable it is.
